Autolus leads winners in spite of scepticism over its CAR-T, and gene therapies disappoint.
The relatively niche cancer setting provides an important battleground for the targeted kinase inhibitor specialists Blueprint Medicines and Loxo Oncology.
Takeda's drug leads the charge of small-molecule tyrosine kinase inhibitors, some of which are very much holding their own against the onslaught of immuno-oncology.
Annual analysis shows a new crop of biotech assets with ballooning valuations and no major partners.
Alnylam has secured its first approval, but history suggests that launch will be far from easy.
A golden age for biotech flotations yielded some spectacular blow-ups, but also saw several groups reward investors with premium-priced takeovers.