AACR 2019 – Foundation Medicine sets the scene for liquid biopsy approval
A study of a liquid biopsy and another looking at tumour mutational burden testing give early indications of Foundation’s approval strategy.
Akebia plays spot the difference with investors
Questions about Akebia's disclosure of liver toxicity in a trial raise a red flag over vadadustat, the company's experimental anaemia treatment.
Two haemophilia A subjects help Sangamo erase 2019's losses
Promising early data with Sangamo and Pfizer’s haemophilia A gene therapy could set up a battle with Roche and Biomarin.
Galapagos flies with more Finch data
Filgotinib could be the safest Jak inhibitor yet, but Galapagos will need to make the most of this as it squares up to Abbvie.
Astra shakes hands with Daiichi to take on Roche
UK group bets billions on an HER2 project slated for late-line patients and those with lower expression of the target protein.
Supernus struggles to gain attention
A phase III failure will do nothing to help Supernus’s SPN-812 compete against generic ADHD drugs.
Fibrocell gets a reality check
Promising data with Fibrocell’s epidermolysis bullosa gene therapy send the company down as funding worries kick in.
Aldeyra seeks to Alleviate worries with conjunctivitis win
Pivotal data validate Aldeyra’s lead project, reproxalap, but there are questions about a lack of dose response.
Astrazeneca and Lexicon’s type 1 diabetes fortunes diverge, for now
Astrazeneca gets one over on Sanofi and Lexicon with European approval for Forxiga. US regulators might not be so forgiving.
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