Four assets with previous rejections are due FDA decisions in February, while those with priority review could become the next string of early approvals.
Biogen’s Alzheimer’s candidate and Fibrogen’s new anaemia pill top the list of the biggest commercial hopes that could reach the market in 2020.
As approval decisions near, further data fail to answer lingering questions about Esperion's bempedoic acid and Amarin's Vascepa.
Amarin and Esperion get a chance to reinforce their lipid-lowering candidates, while a Bayer heart failure project gets a high-profile slot despite its discontinuation.
Data from a fixed-dose combination of bempedoic acid and ezetimibe provides some comfort for investors, but the commercial challenge will remain.
Alnylam has secured its first approval, but history suggests that launch will be far from easy.