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  3. Pharmaceutical Companies
  4. Alligator Bioscience
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January 19, 2022

Asco-GI 2022 – Seagen keeps the faith in souped-up CD40 agonism

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July 22, 2021

Roche takes the Tim-3 battle to Novartis

The Swiss group has likely been paying attention to industry developments as BCMA and CD40 go out, while Covid-19 and Tim-3 move up.

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June 11, 2020

New Genmab/Abbvie tie-up rings old bells

Followers of Nordic Nanovector and Oxford Biomedica, among others, will pay close attention to an early focus of yesterday’s deal.

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June 03, 2020

Asco 2020 movers – cell therapy companies dominate the risers

Adaptimmune and Allogene led numerous cell therapy companies higher over the Asco period, while Cytomx and Arvinas suffered the biggest losses.

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May 15, 2020

Asco 2020 – small-cell lung cancer and the role of CTLA-4

Astra and Merck & Co present mixed small-cell lung cancer data, while Innovent, Xencor, Alphamab and Alligator bang the drum for CTLA-4.

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April 22, 2020

AACR 2020 preview – no Tigit, but plenty of novel mechanisms

Next week’s virtual meeting could resuscitate Ox40 agonists, but an important omission will disappoint.

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July 31, 2019

Another immuno-oncology mechanism threatens to disappoint

As J&J tears up a licensing deal with Alligator, CD40 agonism might join the likes of Ox40 and IDO as an immuno-oncology approach that has failed to deliver.

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June 05, 2019

Asco 2019 event analyser – low-key meeting belies some huge stock moves

Mirati Therapeutics nearly stole the show at Asco despite not actually presenting – a fact that illustrates how low on meaningful data this year's conference was.

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October 10, 2017

Merck’s CTLA4 move – insurance policy or knockout bid?

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July 31, 2017

Opinions split on Ox40

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August 14, 2015

Immuno-oncology collaborations enliven 2015’s dog days

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