2025 Review: Capital’s Better

Biopharma capital returned in 2025. But not for everyone. After a significant dry spell, capital began to flow back into biopharma in 2025. Though not everyone benefited. Deals were fewer but larger. Venture funding rallied late, driven by a small number of outsized rounds. IPO markets stayed largely closed in the US and Europe, while […]

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Biopharma capital returned in 2025. But not for everyone.

After a significant dry spell, capital began to flow back into biopharma in 2025. Though not everyone benefited.

Deals were fewer but larger. Venture funding rallied late, driven by a small number of outsized rounds. IPO markets stayed largely closed in the US and Europe, while Asia continued to pull ahead. Confidence is appropriate – selectively.

In this report, Evaluate examines how 2025 finished across M&A, venture capital and public markets, and what the data reveal about where conviction has truly returned, and where it has not.

Download the report to learn how:

  • M&A regained momentum, with aggregate deal value rising sharply despite lower volumes
  • Late stage conviction returned, as buyers shifted away from bolt ons toward larger, premium transactions
  • Venture funding rebounded in Q4, but full year totals still fell short of 2024
  • Western IPO markets remained constrained, while Asian exchanges continued to absorb new listings
  • Access to capital stayed uneven, reinforcing a widening gap between established and emerging players

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Frequently Asked Questions

The report analyses biopharma M&A, venture capital fundraising and IPO activity during 2025, using Evaluate data to assess where capital returned and where constraints remain.

No. While M&A values rose and venture funding improved late in the year, access to capital remained uneven and Western IPO markets stayed largely closed.

Buyers focused on fewer, higher conviction assets, shifting away from smaller bolt on acquisitions toward larger, premium deals.

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