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Evaluate

January 09, 2023

Arrowhead misses the target in alpha-1 antitrypsin deficiency

The Takeda-partnered project fazirsiran shows an impressive reduction in mutant protein, but questions about fibrosis remain.

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May 09, 2022

Asset resuscitation fails to resuscitate Mereo

Mereo claims another success with a big pharma castoff, but its win in alpha 1-antitrypsin deficiency is questionable.

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May 05, 2022

Jazz overture rekindles hopes for orexin agonism

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November 02, 2021

Centessa claims a place in the antitrypsin deficiency pipeline

But investors will need more convincing; and others are more advanced, with Arrowhead and Inhibrx ones to watch.

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October 05, 2021

Biotech listings show signs of a slowdown

2021 is on track to beat last year’s monster haul, but the IPO window could finally be closing.

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September 30, 2021

Merck & Co justifies paying up for Acceleron

But with the obvious buyer, Bristol, having apparently been outbid, there might be questions over Acceleron’s takeout price.

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September 09, 2021

Centessa takes a step towards a new haemophila mechanism

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July 01, 2021

Biotech listings shows few signs of cooling

IPOs of drug developers raised $9bn in the first half of 2021, a record amount that is hard to square with talk of moderation.

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April 07, 2021

Biotech venture financing starts the year with a bang

With a record $7.1bn raised in the first quarter the cash available to private drug developers shows no signs of drying up.

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