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  4. Product Setback
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Clinical Setback

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May 11, 2022

Looking beyond Roche’s Tigit bombshell

The failure of Skyscraper-01 calls into question Roche’s vast investment in Tigit blockade, but is there broader significance?

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April 26, 2022

Protagonist “delighted” with trial failure

Development of the ulcerative colitis project PN-943 continues.

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April 26, 2022

Late-stage pain pipeline refuses to swell

Setbacks from Eliem, Ampio and Acadia thin an already sparse pain pipeline, which remains lacking in serious interest from big developers.

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April 25, 2022

Roche has a rare breast cancer setback

Giredestrant fails, but the group hopes for better luck in earlier therapy lines.

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April 25, 2022

Gossamer hangs by a thread

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April 20, 2022

First-quarter biotech risers work hard for the win

Amid a difficult start to the year for the drug development sector, Abbvie, Bayer, Ipsen and Lantheus stand out as stock market gainers.

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April 19, 2022

New Nektar needs a pipeline boost

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April 11, 2022

AACR 2022 – A weekend of updates yields few winners

The dour biotech market sees little to be impressed about in updates from Bicycle, Rubius, C4 and Zentalis, though well-received data gives Affimed a boost.

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April 07, 2022

Aptinyx discovers the perils of the data dredge

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April 04, 2022

ACC 2022 – full vupanorsen data shed light on Pfizer’s split

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March 30, 2022

Roche’s Tigit fail poses a big question for Merck

Roche just showed that adding Tigit to PD-(L)1 blockade is a non-starter in SCLC, and now Merck & Co risks doing the same.

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