Vantage Esmo 2021 roundup

Here's a roundup of Vantage's coverage of the 2021 European Society for Medical Oncology congress.

Conferences

September 24

Esmo 2021 movers – a handful of biotech winners emerge

Leap and Innate were clear winners on the stock market during the medical meeting, while Astrazeneca’s strong performance stands out among the large caps.

 

September 22

Astra lays out a grand vision for Enhertu

But proving that the drug’s toxicities are manageable in the real world will become more important as it moves into earlier treatment settings.

 

September 21

Beyondspring experiences winter of discontent

 

September 20

Astra coasts towards a new lung cancer combo

Two new immuno-oncology mechanisms post encouraging data, giving a boost to small developers including Innate and Corvus.

 

September 17

Enhertu sets a very high bar

A move into the larger second-line breast cancer setting is surely on the way for the Astrazeneca and Daiichi drug.

Colorectal cancer could be Mirati’s golden ticket

Adagrasib looks better than Amgen’s Lumakras, which could explain why Mirati has been dragging its heels in lung cancer.

Opdivo’s glimmer of hope in front-line head and neck cancer

The failed Checkmate-651 study hints at a survival benefit in some PD-L1 expressers, but will this be enough to file?

Keytruda challenges Jemperli and adjuvant melanoma

Glaxo’s anti-PD-1 MAb might not have a market niche to itself for long, while a separate trial could help Keytruda double its adjuvant melanoma potential.

Look out Agenus, Keytruda is about to put up a roadblock

Poziotinib could add first-line string to its bow

Mahogany loses its polish for Macrogenics

 

September 16

Astra finally sees a Wee1 signal

It might be too late for adavosertib, but others could benefit if a niche has finally been found for Wee1 inhibitors.

The jury remains out on CDK7 inhibition

Clinical data on Carrick’s samuraciclib and Syros’s SY-5609 show that this mechanism remains a work in progress.

 

September 13

Mirati bids to be belle of the ball (preview)

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